By Douglas Preston, Lincoln Child

Brothers. One, most sensible FBI Agent, Aloysius Pendergast. the opposite, Diogenes, a super and twisted criminal.

An timeless hatred among them.

Now, an ideal crime.

And the last word challenged: cease me in case you can.

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Additional info for Dance of Death (Pendergast, Book 6)

Sample text

The development of the book has been broken down into a short initial treatment of the fundamentals of protein folding in vitro in the absence of molecular chaperones, followed by the main part of the book that focuses on the interaction of proteins with chaperones during various stages of their lives, especially their synthesis and degradation. It is convenient to consider the life of a protein being divided into three parts: birth, maturation, and death. We begin in Chapter 3, with interactions of chaperones with the nascent chain.

A series of cytochrome c species with various extents of acetylation of Lys amino groups was prepared and their conformations were examined [54,55]. , with the Page 14 decrease in protein net charge) and the contribution of charge repulsion in determining the equilibrium between the MG and the unfolded states was estimated. The results indicated that the unfavorable electrostatic repulsive force is proportional to the square root of the protein net charge. Although the charge repulsion is also an important factor of the stability of the native state, that of the native state is much more complicated than that approximated by the net charge.

ISBN 0-8247-0100-3 (hardcover) 1. Molecular chaperonesPhysiological effect. I. Goto, Yuji. II. Title. 645dc21 97-34429 CIP The publisher offers discounts on this book when ordered in bulk quantities. For more information, write to Special Sales/Professional Marketing at the address below. This book is printed on acid-free paper. Copyright © 1998 by MARCEL DEKKER, INC. All Rights Reserved. Neither this book nor any part may be reproduced or transmitted in any form or by any means, electronic or mechanical, including photocopying, microfilming, and recording, or by any information storage and retrieval system, without permission in writing from the publisher.

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